Some good news and bad news. At my rheumatologist visit last Friday I was able to tell her that there's a definite difference in pain relief when I take both methotrexate and Enbrel. I went on Enbrel alone for two weeks (dosing on Fri), was sick about half the weekend, and my relief lasted from about mid-day on Monday-Thursday. By Thursday evening, it's like a wind-up doll that's kaput and someone took out the key. I am toast, and in searing pain.
are nose sores/nose bleeds. Oy, it's annoying and painful at times. Will have to mention that at my next visit.]
So that's the overall good news. The bad news is my last labs showed a spike in some of my liver numbers. MTX affects the liver and there's enough concern that they asked me to come back in 2 weeks for another blood check. I already come once a month for blood work, so my guess is that staying on MTX is in jeopardy if my numbers don't look good.
At night I was toast by about 7:30, and went back to the hotel to crash, re-medicate, apply all my liniments to my sore joints and get in the sack so I could be productive the second day.
I actually had to go into the office the day after the trip; it was questionable whether I was in good enough shape to get my sorry ass into the office, but I did for an important meeting. However, I was out Friday, and then most of the weekend I was in misery, recovering from the travel's impact on my RA and fibromyalgia.
I know for a fact that if I hadn't done the Enbrel/MTX combo, I would have been much worse off post-travel. So, I hope that, despite the pretty nasty MTX side effects, I won't have to discontinue it since it has done some good in getting my constant pain at a liveable, if not enjoyable, level.